[31] Iowa State 10-7 Iowa [4] 2022-09-10 20:00
Stadium: Kinnick Stadium Round: 1
Home Manager: Kirk Ferentz Away Manager: Matt Campbell
Head to Head
| NCAAF | 2021/09/11 20:30 | Iowa v Iowa State | L | 27-17 |
| NCAAF | 2019/09/14 20:00 | Iowa v Iowa State | L | 18-17 |
| NCAAF | 2018/09/08 21:00 | Iowa State v Iowa | L | 3-13 |
| NCAAF | 2017/09/09 16:00 | Iowa v Iowa State | L | 44-41 |
| NCAAF | 2016/09/10 23:30 | Iowa v Iowa State | L | 42-3 |
| NCAAF | 2015/09/12 20:45 | Iowa State v Iowa | L | 17-31 |
| NCAAF | 2014/09/13 19:30 | Iowa v Iowa State | W | 17-20 |
| NCAAF | 2012/09/08 12:00 | Iowa v Iowa State | W | 6-9 |
Home History
| NCAAF | 2022/09/03 18:00 | SE Missouri St v Iowa State | W | 10-42 |
| NCAAF - Bowl Games | 2021/12/29 22:45 | Iowa State v Clemson | L | 13-20 |
| NCAAF | 2021/11/26 21:30 | TCU v Iowa State | W | 14-48 |
| NCAAF | 2021/11/20 17:00 | Iowa State v Oklahoma | L | 21-28 |
| NCAAF | 2021/11/13 20:30 | Iowa State v Texas Tech | L | 38-41 |
| NCAAF | 2021/11/06 23:30 | Texas v Iowa State | W | 7-30 |
| NCAAF | 2021/10/30 18:00 | Iowa State v West Virginia | L | 31-38 |
| NCAAF | 2021/10/23 19:30 | Oklahoma State v Iowa State | W | 21-24 |
Away History
| NCAAF | 2022/09/03 16:00 | South Dakota State v Iowa | W | 3-7 |
| NCAAF - Bowl Games | 2022/01/01 18:00 | Kentucky v Iowa | L | 20-17 |
| NCAAF | 2021/12/05 01:00 | Iowa v Michigan | L | 3-42 |
| NCAAF | 2021/11/26 18:30 | Iowa v Nebraska | W | 28-21 |
| NCAAF | 2021/11/20 19:00 | Illinois v Iowa | W | 23-33 |
| NCAAF | 2021/11/13 20:30 | Minnesota v Iowa | W | 22-27 |
| NCAAF | 2021/11/06 23:00 | Iowa v Northwestern | W | 17-12 |
| NCAAF | 2021/10/30 16:00 | Iowa v Wisconsin | L | 7-27 |
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