Stadium: Shell Energy Stadium Round: 1
| NCAAF | 2022/09/03 23:00 | Texas Southern Tigers v Prairie View | W | 23-40 |
| NCAAF | 2021/09/05 00:00 | Prairie View v Texas Southern Tigers | W | 40-17 |
| NCAAF | 2021/03/07 01:00 | Texas Southern Tigers v Prairie View | W | 19-20 |
| NCAAF | 2019/08/31 22:30 | Prairie View v Texas Southern Tigers | W | 44-23 |
| NCAAF FCS | 2018/11/24 19:00 | Texas Southern Tigers v Prairie View | W | 14-60 |
| NCAAF | 2017/11/26 00:00 | Texas Southern Tigers v Prairie View | W | 16-30 |
| NCAAF | 2022/11/19 19:00 | Prairie View v Mississippi Valley State | L | 7-27 |
| NCAAF | 2022/11/12 20:00 | Prairie View v Arkansas Pine Bluff | W | 55-24 |
| NCAAF | 2022/11/04 23:30 | Alcorn State v Prairie View | L | 23-16 |
| NCAAF | 2022/10/29 19:00 | Bethune Cookman v Prairie View | W | 48-58 |
| NCAAF | 2022/10/22 21:00 | Prairie View v Lamar | W | 54-21 |
| NCAAF | 2022/10/08 21:00 | Southern v Prairie View | L | 45-13 |
| NCAAF | 2022/10/01 23:00 | Prairie View v Grambling State | W | 34-14 |
| NCAAF | 2022/09/24 22:00 | Prairie View v Alabama State | W | 25-15 |
| NCAAF | 2022/11/19 19:00 | Texas Southern Tigers v Alabama | L | 20-24 |
| NCAAF | 2022/11/13 00:00 | Grambling State v Texas Southern Tigers | W | 7-41 |
| NCAAF | 2022/11/05 23:00 | Jackson State v Texas Southern Tigers | L | 41-14 |
| NCAAF | 2022/10/29 19:00 | Texas Southern Tigers v Lincoln Oaklanders | W | 37-2 |
| NCAAF | 2022/10/22 19:00 | Texas Southern Tigers v Alcorn State | W | 34-27 |
| NCAAF | 2022/10/08 19:00 | Texas Southern Tigers v Arkansas Pine Bluff | W | 24-17 |
| NCAAF | 2022/10/01 23:00 | Alabama State v Texas Southern Tigers | L | 16-13 |
| NCAAF | 2022/09/24 19:30 | Texas Southern Tigers v Texas-San Antonio | L | 24-52 |