Stadium: Longley Athletic Complex Round: 1
| NCAAF | 2022/11/05 16:00 | Dean Bulldogs v Anna Maria Amcats | L | 22-36 |
| NCAAF | 2022/10/29 18:00 | Suny Maritime Privateers v Dean Bulldogs | L | 30-19 |
| NCAAF | 2022/10/22 16:00 | Alfred State Pioneers v Dean Bulldogs | W | 35-36 |
| NCAAF | 2022/10/15 16:00 | Dean Bulldogs v Gallaudet Bison | L | 23-26 |
| NCAAF | 2022/10/01 21:00 | Castleton Spartans v Dean Bulldogs | L | 39-0 |
| NCAAF | 2022/09/24 17:15 | Mit Engineers v Dean Bulldogs | L | 35-6 |
| NCAAF | 2022/09/17 16:00 | Dean Bulldogs v Curry Colonels | L | 25-33 |
| NCAAF | 2022/09/09 22:00 | Nichols Bison v Dean Bulldogs | L | 71-55 |
| NCAAF | 2022/11/05 17:00 | Keystone Giants v Suny Maritime Privateers | W | 21-20 |
| NCAAF | 2022/10/22 16:00 | Keystone Giants v Castleton Spartans | L | 20-35 |
| NCAAF | 2022/10/15 16:00 | Anna Maria Amcats v Keystone Giants | W | 39-41 |
| NCAAF | 2022/10/08 17:00 | Alfred State Pioneers v Keystone Giants | L | 42-33 |
| NCAAF | 2022/10/01 16:00 | Keystone Giants v Gallaudet Bison | L | 44-52 |
| NCAAF | 2022/09/24 17:30 | Keystone Giants v Hobart Statesmen | L | 6-65 |
| NCAAF | 2022/09/17 17:00 | William Paterson Pioneers v Keystone Giants | L | 27-20 |
| NCAAF | 2022/09/10 17:00 | Misericordia Cougars v Keystone Giants | L | 38-20 |