| Wimbledon - ženy | 06/28 14:45 | 15 | [112] Oceane Dodin v Despina Papamichail [188] | 6-7,6-7 | |
| Wimbledon - ženy | 06/27 12:50 | 14 | [207] Zeynep Sonmez v Despina Papamichail [188] | 3-6,6-3,4-6 | |
| ITF - W40 Ystad | 06/21 11:50 | 25 | [437] Julia Middendorf v Despina Papamichail [189] | 7-5,4-6,7-6 | |
| ITF - W60 Říčany | 06/15 08:00 | 26 | [175] Despina Papamichail v Seone Mendez [369] | 2-6,7-5,3-6 | |
| ITF - W60 Říčany | 06/14 09:40 | 25 | [175] Despina Papamichail v Amina Anshba [389] | 6-2,6-3 | |
| ITF - W60 Caserta | 06/07 11:00 | 25 | [158] Despina Papamichail v Vivian Wolff [493] | 2-6,3-6 | |
| ITF - W60 Brescia | 06/01 09:00 | 26 | [158] Despina Papamichail v Yuliya Hatouka [263] | 4-6,2-6 | |
| ITF - W60 Brescia | 05/31 07:30 | 25 | Despina Papamichail v Claudia Hoste Ferrer | 6-2,6-3 | |
| French Open - ženy | 05/23 08:00 | 14 | [157] Despina Papamichail v Moyuka Uchijima [145] | 2-6,2-6 | |
| ITF - W100 Madrid | 05/16 08:50 | 25 | [183] Mai Hontama v Despina Papamichail [157] | 6-4,6-1 | |
| WTA - Rím | 05/08 09:35 | 14 | [107] Arantxa Rus v Despina Papamichail [157] | 6-2,6-1 | |
| WTA - Saint-Malo | 05/02 09:00 | 25 | Elina Svitolina v Despina Papamichail | 7-5,6-1 | |
| WTA - Madrid | 04/24 10:35 | 14 | [76] Nuria Parrizas-Diaz v Despina Papamichail [152] | 7-6,6-2 | |
| Billie Jean King Cup | 04/15 11:30 | 2 | [69] Anett Kontaveit v Despina Papamichail [151] | 2-6,4-6 | |
| Billie Jean King Cup | 04/14 11:40 | 2 | [151] Despina Papamichail v Francisca Jorge [314] | 5-7,6-7 | |
| Billie Jean King Cup | 04/13 10:50 | - | [151] Despina Papamichail v Nefisa Berberovic [319] | 4-6,4-6 | |
| Billie Jean King Cup | 04/12 11:50 | 2 | Despina Papamichail v Francesca Curmi | 6-4,6-7,4-6 | |
| Billie Jean King Cup | 04/11 11:15 | 2 | [151] Despina Papamichail v Lina Glushko [271] | 6-1,6-1 | |
| WTA - Bogota | 04/04 17:40 | 25 | [152] Despina Papamichail v Nuria Brancaccio [206] | 2-6,2-6 | |
| WTA - San Luis Potosi | 03/29 00:25 | 25 | [151] Despina Papamichail v Aliona Bolsova [152] | 1-6,6-3,4-6 | |
| WTA - Monterrey | 02/27 19:50 | 25 | [150] Despina Papamichail v Ysaline Bonaventure [96] | 6-7,6-4,1-6 | |
| WTA - Monterrey | 02/26 18:30 | 19 | [126] Marina B Ribera v Despina Papamichail [151] | 4-6,4-6 | |
| WTA - Monterrey | 02/25 22:30 | 14 | Lya I F Olivares v Despina Papamichail | 1-6,1-6 | |
| WTA - Merida | 02/18 21:40 | 14 | [108] Leolia Jeanjean v Despina Papamichail [155] | 7-5,1-6,6-3 | |
| ITF - W60 Irapuato | 02/16 20:30 | 26 | [67] Xinyu Wang v Despina Papamichail [155] | 4-6,6-4,7-6 | |
| ITF - W60 Irapuato | 02/15 22:10 | 25 | [362] Ana Sofia Sanchez v Despina Papamichail [155] | 3-6,4-6 | |
| ITF - W40 Mexico City | 02/09 16:30 | 27 | [368] Jana Kolodynska v Despina Papamichail [154] | 6-3,7-6 | |
| ITF - W40 Mexico City | 02/08 16:30 | 26 | [280] Sofia Sewing v Despina Papamichail [154] | 2-6,5-7 | |
| ITF - W40 Mexico City | 02/07 15:30 | 25 | [364] Sofia Costoulas v Despina Papamichail [154] | 6-7,2-6 | |
| ITF - W40 Mexico City | 02/03 17:00 | 28 | [346] Berfu Cengiz v Despina Papamichail [151] | 6-7,6-4,6-3 |
Despina Papamichail (Greek: Δέσποινα Παπαμιχαήλ; born 9 February 1993) is a Greek professional tennis player. She has a career-high singles ranking of world No. 147, reached on 20 June 2022. Her highest doubles ranking is No. 93, achieved on 4 December 2023. Papamichail has won two doubles titles on the WTA Challenger Tour as well as 15 singles and 37 doubles titles on the ITF Women's Circuit.
Playing for the Greece Fed Cup team, Papamichail has a win–loss record of 31–29 (as of May 2024).
In June 2021, Papamichail won the inaugural $60k Charleston Pro event by defeating Gabriela Cé, her first title above $25k level.
She made her WTA Tour main-draw debut 2021 at the WTA 500 event in Abu Dhabi.
At the 2023 United Cup, she started the season with a win over Isabella Shinikova.
Later, she qualified for the Pan Pacific Open and defeated lucky loser Sakura Hosogi.